Preimplantation genetic screening- the required RCT that has not yet been carried out

Preimplantation genetic screening- the required RCT that has not yet been carried out

The utilization of trophectoderm biopsy combined with comprehensive chromosome screening (CCS) tests for embryonic aneuploidy was recently suggested to improve IVF outcome, however, not without criticisms. The ongoing discussion on the unrestricted clinical adoption of preimplantation genetic screening (PGS) has called for a proper randomized controlled trial (RCT), aiming to further evaluate t...

Preimplantation genetic screening.

Preimplantation Genetic Screening

In the last 30 years, genetic testing techniques have been developed to identify chromosomally normal embryos in vitro, thereby potentially increasing the proportion of successful cycles with elective single-embryo transfer, and minimizing twin-pregnancy complications and miscarriages. This testing is termed "pre-implantation genetic screening" (PGS), in contrast to preimplantation genetic diag...

Databases for Software Engineering Environments - The Goal has not yet been attained

We argue that, despite a substantial number of proposed and existing new database systems, a suitable database system for software development environments and especially process-centred environments does not yet exist. We do so by reviewing and re ning the requirements for such systems in detail based on a number of examples. We then sketch a number of available and archetypical database syste...

Immune checkpoint inhibitors in lung cancer: the holy grail has not yet been found…

1Phase I Early Clinical Trials Unit, Department of Oncology, Universitair Ziekenhuis Antwerpen, Edegem, Belgium 2Consorci Hospital General Universitari de Valencia, Valencia, Comunitat Valenciana, Spain 3Early Development Drugs Unit, Medical Oncology Department, Instituto Oncológico Fundación Arturo López Pérez, Santiago, Chile 4Department of Oncology, Universita degli Studi di Palermo, Palermo...